FORMULATION AND EVALUATION OF CARICA PAPAYA AND NICOTIANA TABACUM CONTAINING SHAMPOO FOR ANTI-TICKS ACTIVITY
Abstract
The aim of this research was to formulate and evaluate shampoo containing Carica Papaya and Nicotiana Tabacum as a chief herbal drug for the acaricidal activity. Carica Papaya and Nicotiana Tabacum known for their anti-inflammatory, antioxidant, diuretic, antibacterial, vermifuge, hypoglycemic, antifungal activity, antihelmenthic and immunomodulatory activity, respectively. The shampoo formulations were formulated using extracts of Carica Papaya and Nicotiana Tabacum leaf. The formulated shampoo was evaluated for visual appearance, ph, physicochemical characterization, solid content, surface tension, foam volume, foam stability and Anti-Ticks Activity Of Shampoo. Ethanolic Extract of Carica Papaya and Nicotiana Tabacum leaf were taken for in acaricidal activity against ticks. Different concentrations (2%, 4%, 6%) of plants extracts were used for the anti-ticks activity and Shampoo concentration (2.5%, 5%, and 10%) were used for activity. shampoo was compared against standard Amitraz. Normal water was used for the control treatment. Carica Papaya and Nicotiana Tabacum leaf Shampoo showed 100% mortality rate within 04 minutes while standard takes 15 minutes. The results obtained from the study indicate the strong anti-ticks activity, supporting folk use of the plants when compared with the standard. Both the extracts of Carica Papaya and Nicotiana Tabacum leaf Shampoo were found to show a potent Acaricidal effect better than standard amitraz.